By default, GNOME will reboot the system if the
Ctrl-Alt-Del key sequence is pressed.
To configure the system to ignore the Ctrl-Alt-Del key sequence
from the Graphical User Interface (GUI) instead of rebooting the system,
add or set logout to '' in
/etc/dconf/db/local.d/00-security-settings. For example:
[org/gnome/settings-daemon/plugins/media-keys]
logout=''
Once the settings have been added, add a lock to
/etc/dconf/db/local.d/locks/00-security-settings-lock to prevent
user modification. For example:
/org/gnome/settings-daemon/plugins/media-keys/logout
After the settings have been set, run dconf update.